Showing posts with label salt. Show all posts
Showing posts with label salt. Show all posts

Monday, June 8, 2009

Reduced cardiovascular health

The heart often pumps blood less efficiently in older people, usually because of insufficient physical activity. Poor heart conditioning allows fatty and connective tissues to infiltrate the heart’s muscular wall. However, this decline in cardiac output is not inevitable with aging and does not occur among older people who remain physically active. In fact, it is thought that the inactive lifestyles of nearly 60% of North American adults may contribute as much to the risk for cardiovascular disease as smoking a pack of cigarettes per day.

Heart attack and stroke, 2 of the 3 major causes of death in adults, are caused primarily by atherosclerosis and hypertension. As we age, atherosclerotic plaque accumulates in the arteries, reducing their elasticity, constricting blood flow, and consequently elevating blood pressure.

You already know the main way to limit the buildup of atherosclerotic plaque: Keep LDL-cholesterol and the total cholesterol/HDL-cholesterol ratio in the desirable range. New evidence shows that a diet very low in fat can cause some plaques to decrease in size. Other studies use diet and medications to lower blood cholesterol, which in urn reduces the amount of plaque in the arteries supplying the heart. This suggests that a heart-healthy diet is more important during middle to late adulthood than researchers previously thought. Consuming sufficient vitamin B-6, folate, and vitamin B-12 are also important to avoid elevated blood homocysteine, a probable risk factor for cardiovascular disease.

Much controversy surrounds the treatment for elevated LDL-cholesterol in people over the age of 70. If these people adhere to extremely restrictive diets limited in fat and energy to the point that they can’t keep up their weight, or if their diets lack variety, they may become undernourished. This may be a worse predicament for them than having high LDL-cholesterol. Therefore, treating elevated LDL-cholesterol in an older person who ahs other illnesses, such as chronic lung disease and dementia (which are likely to shorten life as well as hamper its quality) is probably inappropriate. However, if a healthy 70 year old who is likely to live another 10 to 15 years has both elevated LDL-cholesterol and evidence of cardiovascular disease, an eating and exercise plan is probably in order to reduce the chance of heart attack.

Hypertension is heavily implicated in both stroke and heart attack in older adults. Blood pressure can be lowered in many people by restricting salt intake. A limit of 2400mg of sodium per day helps many people with hypertension, but that is a difficult diet to plan and follow for older people who rely on convenience foods. Alternatively, a mild sodium restriction (not to exceed 4000mg of sodium daily) may be effective for salt-sensitive people but is not so helpful by itself for those who have hypertension that hypertension.

We can do much to prevent heart attack and stroke just by eating a balanced diet, walking briskly and otherwise performing regular physical activity, controlling blood pressure, not smoking, and maintaining healthy weight. Regular physical activity and a diet rich in fruits and vegetables are also associated with fewer strokes as adults age, as is a moderate use of alcohol.

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Sunday, April 19, 2009

Salt and blood pressure

Excess salt intake tends to increase blood pressure, particularly in African Americans, older persons, obese persons, and people in general who are susceptible to developing a problem regulating sodium concentration in the body. This last group is termed “sodium sensitive” because they are not good at excreting excess salt via the kidney. This excess salt retention has some tendency to increase blood pressure in these people. It is not clear whether the sodium ion or the chloride ion is most responsible for the effect. If one reduces sodium intake, chloride intake naturally falls; the opposite is also true. For the most part, when nutrition recommendations suggest consuming less sodium that is equivalent to saying consume less salt. Since only some North Americans are very susceptible to increase in blood pressure from salt intake, it is likely only the lifestyle factor related to hypertension. Thus, it is unfortunate that salt intake receives the major portion of public attention with regard to hypertension; obesity, inactivity, and alcohol abuse should be given much more attention. This is especially true for people who are not sodium sensitive. Again, about half the people with hypertension are not. However, many people with hypertension do not know whether they are not sodium sensitive, and testing for this sensitivity takes a lot of time and is not routinely done.

The latest dietary advice from the Dietary Guidelines for Americans and the American Heart Association suggests that adults consume no more than the Daily Value for sodium (2400 mg). Currently, North Americans consume daily, an average, almost double that amount (4 to 7 g). Both sets of recommendations note that there is no risk in reducing sodium intake to the Daily Value.

The exact mechanism whereby sodium increases blood pressure is not clear. Studies suggest that there is a genetically influenced ability that determines the ease at which the body can excrete sodium. In salt sensitive individuals, the kidneys require a higher blood pressure in order to excrete sodium from the body, compared with salt-resistant people. This causes salt-sensitive individuals to retain more sodium. This sodium retention in the body then leads to increased blood volume and, in turn, the increased blood pressure needed to maintain sodium excretion.

Physicians usually resort to a combination of antihypertensive medications, such as diuretics and modern sodium restriction (3-4g/day) as an initial form of therapy. This combination typically reduces blood volume, and therefore, is often effective in controlling blood pressure.

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